Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor.

Prostanoid receptors belong to the class of heptahelical plasma membrane receptors. For the five prostanoids, eight receptor subtypes have been identified. They display an overall sequence similarity of roughly 30%. Based on sequence comparison, single amino acids in different subtypes of different...

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Autores principales: Neuschäfer-Rube, Frank, Engemaier, Eva, Koch, Sina, Böer, Ulrike, Püschel, Gerhard P
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223288/
https://ncbi.nlm.nih.gov/pubmed/12519077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021429
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