Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7.

Several integrin alpha subunits undergo post-translational endoproteolytic processing at pairs of basic amino acids that is mediated by the proprotein convertase furin. Here we ask whether other convertase family members can participate in these processing events. We therefore examined the endoprote...

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Detalhes bibliográficos
Main Authors: Lissitzky, J C, Luis, J, Munzer, J S, Benjannet, S, Parat, F, Chrétien, M, Marvaldi, J, Seidah, N G
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220832/
https://ncbi.nlm.nih.gov/pubmed/10657249
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