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Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours.

Proprotein convertases mediate the production of a variety of peptidic mitogens by limited proteolysis of their precursors. These proteases may also participate in the autocrine production of such mitogens by cancer cells and thus contribute to the unchecked proliferation of these cells. As a step t...

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Detalhes bibliográficos
Main Authors: Mbikay, M., Sirois, F., Yao, J., Seidah, N. G., Chrétien, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223512/
https://ncbi.nlm.nih.gov/pubmed/9166946
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