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Enzymic characterization in vitro of recombinant proprotein convertase PC4.

Proprotein convertase PC4A, a member of the subtilisin/kexin family of serine proteases, was obtained in enzymically active form following expression of vaccinia virus recombinant rat (r)PC4A in GH4C1 cells. It displayed maximal activity at pH 7.0 and a Ca(2+) concentration of 2.0 mM. Using PC4-spec...

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Hlavní autoři: Basak, A, Touré, B B, Lazure, C, Mbikay, M, Chrétien, M, Seidah, N G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220520/
https://ncbi.nlm.nih.gov/pubmed/10493908
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