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PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

A recombinant vaccinia virus vector was used to coexpress the two candidate mouse prohormone convertases, PC1 and PC2, together with mouse proopiomelanocortin (POMC) in the constitutively secreting cell line BSC-40 and in the endocrine tissue-derived cell lines PC12 and AtT-20, which exhibit regulat...

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Библиографические подробности
Главные авторы: Benjannet, S, Rondeau, N, Day, R, Chrétien, M, Seidah, N G
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC51492/
https://ncbi.nlm.nih.gov/pubmed/2023902
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