Akt, a Target of Phosphatidylinositol 3-Kinase, Inhibits Apoptosis in a Differentiating Neuronal Cell Line

Phosphatidylinositol (PI) 3-kinase has been suggested to mediate cell survival. Consistent with this possibility, apoptosis of conditionally (simian virus 40 T(ts)) immortalized rat hippocampal H19-7 neuronal cells was increased in response to wortmannin, an inhibitor of PI 3-kinase. Downstream effe...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Eves, Eva M., Xiong, Wen, Bellacosa, Alfonso, Kennedy, Scott G., Tsichlis, Philip N., Rosner, Marsha Rich, Hay, Nissim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2143
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