Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

The interleukin-2 (IL-2) receptor (IL-2R) is composed of three subunits. Of these, IL-2Rα is required for high-affinity IL-2 binding, while IL-2Rβ and IL-2Rγ(c) are required for the transduction of IL-2-generated signals. Signals transduced via the S region of the IL-2Rβ (amino acids 267–322) in BAF...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ahmed, Naheed N., Grimes, H. Leighton, Bellacosa, Alfonso, Chan, Tung O., Tsichlis, Philip N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20491/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108028/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3627
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