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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

The interleukin-2 (IL-2) receptor (IL-2R) is composed of three subunits. Of these, IL-2Rα is required for high-affinity IL-2 binding, while IL-2Rβ and IL-2Rγ(c) are required for the transduction of IL-2-generated signals. Signals transduced via the S region of the IL-2Rβ (amino acids 267–322) in BAF...

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Autores principales: Ahmed, Naheed N., Grimes, H. Leighton, Bellacosa, Alfonso, Chan, Tung O., Tsichlis, Philip N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC20491/
https://ncbi.nlm.nih.gov/pubmed/9108028
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