Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

Hepatocyte growth factor (HGF) is a ligand of the receptor tyrosine kinase encoded by the c-Met protooncogene. HGF/Met signaling has multifunctional effects on various cell types. We sought to determine the role of HGF/Met in apoptosis and identify signal transducers involved in this process. In exp...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Xiao, Guang-Hui, Jeffers, Michael, Bellacosa, Alfonso, Mitsuuchi, Yasuhiro, Vande Woude, George F., Testa, Joseph R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011532898
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