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Calcineurin Triggers Reactive/Inflammatory Processes in Astrocytes and Is Upregulated in Aging and Alzheimer's Models

Astrocyte reactivity (i.e., activation) and associated neuroinflammation are increasingly thought to contribute to neurodegenerative disease. However, the mechanisms that trigger astrocyte activation are poorly understood. Here, we studied the Ca(2+)-dependent phosphatase calcineurin, which regulate...

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書誌詳細
主要な著者: Norris, Christopher M., Kadish, Inga, Blalock, Eric M., Chen, Kuey-Chu, Thibault, Veronique, Porter, Nada M., Landfield, Philip W., Kraner, Susan D.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201418/
https://ncbi.nlm.nih.gov/pubmed/15872113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0365-05.2005
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