Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca(2+)-Dysregulation Aging Phenotype in Hippocampal Neurons

With aging, multiple Ca(2+)-associated electrophysiological processes exhibit increased magnitude in hippocampal pyramidal neurons, including the Ca(2+)-dependent slow afterhyperpolarization (sAHP), L-type voltage-gated Ca(2+) channel (L-VGCC) activity, Ca(2+)-induced Ca(2+) release (CICR) from ryan...

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Main Authors: Gant, John C., Chen, Kuey-Chu, Norris, Christopher M., Kadish, Inga, Thibault, Olivier, Blalock, Eric M., Porter, Nada M., Landfield, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092371/
https://ncbi.nlm.nih.gov/pubmed/21289178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4805-10.2011
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