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Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory Impairment

Multiple hippocampal processes and cognitive functions change with aging or Alzheimer's disease, but the potential triggers of these aging cascades are not well understood. Here, we quantified hippocampal expression profiles and behavior across the adult lifespan to identify early aging changes...

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Detalhes bibliográficos
Main Authors: Kadish, Inga, Thibault, Olivier, Blalock, Eric M., Chen, Kuey-C., Gant, John C., Porter, Nada M., Landfield, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661568/
https://ncbi.nlm.nih.gov/pubmed/19211887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4599-08.2009
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