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Decreased G-Protein-Mediated Regulation and Shift in Calcium Channel Types with Age in Hippocampal Cultures

The membrane density of L-type voltage-sensitive Ca(2+) channels (L-VSCCs) of rat hippocampal neurons increases over age [days in vitro (DIV)] in long-term primary cultures, apparently contributing both to spontaneous cell death and to enhanced excitotoxic vulnerability. Similar increases in L-VSCCs...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Blalock, Eric M., Porter, Nada M., Landfield, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783042/
https://ncbi.nlm.nih.gov/pubmed/10493768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08674.1999
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