Calcineurin Triggers Reactive/Inflammatory Processes in Astrocytes and Is Upregulated in Aging and Alzheimer's Models

Astrocyte reactivity (i.e., activation) and associated neuroinflammation are increasingly thought to contribute to neurodegenerative disease. However, the mechanisms that trigger astrocyte activation are poorly understood. Here, we studied the Ca(2+)-dependent phosphatase calcineurin, which regulate...

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Detalhes bibliográficos
Main Authors: Norris, Christopher M., Kadish, Inga, Blalock, Eric M., Chen, Kuey-Chu, Thibault, Veronique, Porter, Nada M., Landfield, Philip W., Kraner, Susan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201418/
https://ncbi.nlm.nih.gov/pubmed/15872113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0365-05.2005
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