CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Clin Diagn Lab Immunol
Principais autores:	Itoh, Naoto, Nishimura, Hitoshi, Matsuguchi, Tetsuya, Yajima, Toshiki, Mokuno, Yasuji, Hiromatsu, Takashi, Nimura, Yuji, Yoshikai, Yasunobu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Cellular Immunology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC119987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11986258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.9.3.550-557.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!