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CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality
Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC119987/ https://ncbi.nlm.nih.gov/pubmed/11986258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.3.550-557.2002 |
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