CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...

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Bibliografske podrobnosti

izdano v:	Clin Diagn Lab Immunol
Principais autores:	Itoh, Naoto, Nishimura, Hitoshi, Matsuguchi, Tetsuya, Yajima, Toshiki, Mokuno, Yasuji, Hiromatsu, Takashi, Nimura, Yuji, Yoshikai, Yasunobu
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Cellular Immunology
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC119987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11986258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.9.3.550-557.2002
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