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CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Itoh, Naoto, Nishimura, Hitoshi, Matsuguchi, Tetsuya, Yajima, Toshiki, Mokuno, Yasuji, Hiromatsu, Takashi, Nimura, Yuji, Yoshikai, Yasunobu
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC119987/
https://ncbi.nlm.nih.gov/pubmed/11986258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.3.550-557.2002
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