CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...

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Argitaratua izan da:	Clin Diagn Lab Immunol
Egile Nagusiak:	Itoh, Naoto, Nishimura, Hitoshi, Matsuguchi, Tetsuya, Yajima, Toshiki, Mokuno, Yasuji, Hiromatsu, Takashi, Nimura, Yuji, Yoshikai, Yasunobu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2002
Gaiak:	Cellular Immunology
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC119987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11986258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.9.3.550-557.2002
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