CD8α-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Intestinal intraepithelial lymphocytes (i-IEL) expressing CD8α are located in the intestine and may confer protection against invasion of intestinal microflora. We found that mice rendered deficient in CD8α molecules by homologous recombination were susceptible to 5-fluorouracil (5-FU)-induced letha...

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Dades bibliogràfiques

Publicat a:	Clin Diagn Lab Immunol
Autors principals:	Itoh, Naoto, Nishimura, Hitoshi, Matsuguchi, Tetsuya, Yajima, Toshiki, Mokuno, Yasuji, Hiromatsu, Takashi, Nimura, Yuji, Yoshikai, Yasunobu
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Cellular Immunology
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC119987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11986258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.9.3.550-557.2002
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