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Inactivation of Sterol Δ(5,6)-Desaturase Attenuates Virulence in Candida albicans
Two clinical Candida albicans isolates that exhibited high-level resistance to azoles and modest decreases in susceptibility to amphotericin B were cultured from unrelated patients. Both isolates harbored homozygous nonsense mutations in ERG3, which encodes an enzyme, sterol Δ(5,6)-desaturase, invol...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1195422/ https://ncbi.nlm.nih.gov/pubmed/16127034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3646-3651.2005 |
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