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Alpha/Beta Interferon Differentially Modulates the Clearance of Cytoplasmic Encapsidated Replication Intermediates and Nuclear Covalently Closed Circular Hepatitis B Virus (HBV) DNA from the Livers of Hepatocyte Nuclear Factor 1α-Null HBV Transgenic Mice

Treatment with alpha interferon is a standard therapy for patients with chronic hepatitis B virus (HBV) infections. This treatment can reduce virus load and ameliorate disease symptoms. However, in the majority of cases, alpha interferon therapy fails to resolve the chronic HBV infection. The reason...

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Main Authors: Anderson, Aimee L., Banks, Krista E., Pontoglio, Marco, Yaniv, Moshe, McLachlan, Alan
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193586/
https://ncbi.nlm.nih.gov/pubmed/16103155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11045-11052.2005
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