Alpha/Beta Interferon Differentially Modulates the Clearance of Cytoplasmic Encapsidated Replication Intermediates and Nuclear Covalently Closed Circular Hepatitis B Virus (HBV) DNA from the Livers of Hepatocyte Nuclear Factor 1α-Null HBV Transgenic Mice

Treatment with alpha interferon is a standard therapy for patients with chronic hepatitis B virus (HBV) infections. This treatment can reduce virus load and ameliorate disease symptoms. However, in the majority of cases, alpha interferon therapy fails to resolve the chronic HBV infection. The reason...

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Detalhes bibliográficos
Main Authors: Anderson, Aimee L., Banks, Krista E., Pontoglio, Marco, Yaniv, Moshe, McLachlan, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193586/
https://ncbi.nlm.nih.gov/pubmed/16103155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11045-11052.2005
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