Alpha/Beta Interferon Differentially Modulates the Clearance of Cytoplasmic Encapsidated Replication Intermediates and Nuclear Covalently Closed Circular Hepatitis B Virus (HBV) DNA from the Livers of Hepatocyte Nuclear Factor 1α-Null HBV Transgenic Mice

Treatment with alpha interferon is a standard therapy for patients with chronic hepatitis B virus (HBV) infections. This treatment can reduce virus load and ameliorate disease symptoms. However, in the majority of cases, alpha interferon therapy fails to resolve the chronic HBV infection. The reason...

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Autores principales: Anderson, Aimee L., Banks, Krista E., Pontoglio, Marco, Yaniv, Moshe, McLachlan, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193586/
https://ncbi.nlm.nih.gov/pubmed/16103155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11045-11052.2005
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