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Hepatocyte Nuclear Factor 3β Inhibits Hepatitis B Virus Replication In Vivo

Hepatitis B virus (HBV) transgenic mice expressing rat hepatocyte nuclear factor 3β (HNF3β) were generated by breeding HBV transgenic mice with transgenic mice that constitutively overexpress the rat HNF3β polypeptide in the liver. HBV 3.5-, 2.4- and 2.1-kb transcripts were reduced 2- to 4-fold in t...

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Detalhes bibliográficos
Main Authors: Banks, Krista E., Anderson, Aimee L., Tang, Hong, Hughes, Douglas E., Costa, Robert H., McLachlan, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136732/
https://ncbi.nlm.nih.gov/pubmed/12438623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12974-12980.2002
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