Hepatocyte Nuclear Factor 3β Inhibits Hepatitis B Virus Replication In Vivo

Hepatitis B virus (HBV) transgenic mice expressing rat hepatocyte nuclear factor 3β (HNF3β) were generated by breeding HBV transgenic mice with transgenic mice that constitutively overexpress the rat HNF3β polypeptide in the liver. HBV 3.5-, 2.4- and 2.1-kb transcripts were reduced 2- to 4-fold in t...

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Bibliografiske detaljer
Main Authors: Banks, Krista E., Anderson, Aimee L., Tang, Hong, Hughes, Douglas E., Costa, Robert H., McLachlan, Alan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136732/
https://ncbi.nlm.nih.gov/pubmed/12438623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12974-12980.2002
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