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Hepatocyte Nuclear Factor 3β Inhibits Hepatitis B Virus Replication In Vivo

Hepatitis B virus (HBV) transgenic mice expressing rat hepatocyte nuclear factor 3β (HNF3β) were generated by breeding HBV transgenic mice with transgenic mice that constitutively overexpress the rat HNF3β polypeptide in the liver. HBV 3.5-, 2.4- and 2.1-kb transcripts were reduced 2- to 4-fold in t...

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Main Authors: Banks, Krista E., Anderson, Aimee L., Tang, Hong, Hughes, Douglas E., Costa, Robert H., McLachlan, Alan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136732/
https://ncbi.nlm.nih.gov/pubmed/12438623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12974-12980.2002
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