Alpha/Beta Interferon Differentially Modulates the Clearance of Cytoplasmic Encapsidated Replication Intermediates and Nuclear Covalently Closed Circular Hepatitis B Virus (HBV) DNA from the Livers of Hepatocyte Nuclear Factor 1α-Null HBV Transgenic Mice

Treatment with alpha interferon is a standard therapy for patients with chronic hepatitis B virus (HBV) infections. This treatment can reduce virus load and ameliorate disease symptoms. However, in the majority of cases, alpha interferon therapy fails to resolve the chronic HBV infection. The reason...

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Autors principals: Anderson, Aimee L., Banks, Krista E., Pontoglio, Marco, Yaniv, Moshe, McLachlan, Alan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193586/
https://ncbi.nlm.nih.gov/pubmed/16103155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11045-11052.2005
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