Impaired Urea Accumulation in the Inner Medulla of Mice Lacking the Urea Transporter UT-A2

Urea transporter UT-A2, the major urea transporter of the thin descending limb of the loop of Henle in short loop nephrons, has been implicated in urea recycling in the medulla, thereby producing concentrated urine. To investigate the physiological role of UT-A2 in vivo, we generated UT-A2-selective...

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Bibliographische Detailangaben
Hauptverfasser: Uchida, Shinichi, Sohara, Eisei, Rai, Tatemitsu, Ikawa, Masahito, Okabe, Masaru, Sasaki, Sei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190230/
https://ncbi.nlm.nih.gov/pubmed/16055743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7357-7363.2005
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