Impaired Urea Accumulation in the Inner Medulla of Mice Lacking the Urea Transporter UT-A2

Urea transporter UT-A2, the major urea transporter of the thin descending limb of the loop of Henle in short loop nephrons, has been implicated in urea recycling in the medulla, thereby producing concentrated urine. To investigate the physiological role of UT-A2 in vivo, we generated UT-A2-selective...

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Detalhes bibliográficos
Main Authors: Uchida, Shinichi, Sohara, Eisei, Rai, Tatemitsu, Ikawa, Masahito, Okabe, Masaru, Sasaki, Sei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190230/
https://ncbi.nlm.nih.gov/pubmed/16055743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7357-7363.2005
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