Impaired Urea Accumulation in the Inner Medulla of Mice Lacking the Urea Transporter UT-A2

Urea transporter UT-A2, the major urea transporter of the thin descending limb of the loop of Henle in short loop nephrons, has been implicated in urea recycling in the medulla, thereby producing concentrated urine. To investigate the physiological role of UT-A2 in vivo, we generated UT-A2-selective...

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Hlavní autoři: Uchida, Shinichi, Sohara, Eisei, Rai, Tatemitsu, Ikawa, Masahito, Okabe, Masaru, Sasaki, Sei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190230/
https://ncbi.nlm.nih.gov/pubmed/16055743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7357-7363.2005
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