تحميل...
IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities
In iron-starved cells, IRP1 (iron regulatory protein 1) binds to mRNA iron-responsive elements and controls their translation or stability. In response to increased iron levels, RNA-binding is inhibited on assembly of a cubane [4Fe-4S] cluster, which renders IRP1 to a cytosolic aconitase. Phosphoryl...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Portland Press Ltd.
2005
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186702/ https://ncbi.nlm.nih.gov/pubmed/15636585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041623 |
| الوسوم: |
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