Control of liver cell fate decision by a gradient of TGFβ signaling modulated by Onecut transcription factors

During liver development, hepatocytes and biliary cells differentiate from common progenitors called hepatoblasts. The factors that control hepatoblast fate decision are unknown. Here we report that a gradient of activin/TGFβ signaling controls hepatoblast differentiation. High activin/TGFβ signalin...

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Bibliografiske detaljer
Main Authors: Clotman, Frédéric, Jacquemin, Patrick, Plumb-Rudewiez, Nicolas, Pierreux, Christophe E., Van der Smissen, Patrick, Dietz, Harry C., Courtoy, Pierre J., Rousseau, Guy G., Lemaigre, Frédéric P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2005
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186184/
https://ncbi.nlm.nih.gov/pubmed/16103213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.340305
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