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Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

Previously, we have shown that Onecut1 (Oc1) and Onecut2 (Oc2) are expressed in retinal progenitor cells, developing retinal ganglion cells (RGCs), and horizontal cells (HCs). However, in Oc1-null mice, we only observed an 80% reduction in HCs, but no defects in other cell types. We postulated that...

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Autors principals: Sapkota, Darshan, Chintala, Hemabindu, Wu, Fuguo, Fliesler, Steven J., Hu, Zihua, Mu, Xiuqian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191802/
https://ncbi.nlm.nih.gov/pubmed/25228773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405354111
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