Threshold Levels of Hepatocyte Nuclear Factor 6 (HNF-6) Acting in Synergy with HNF-4 and PGC-1α Are Required for Time-Specific Gene Expression during Liver Development

During liver development, hepatocytes undergo a maturation process that leads to the fully differentiated state. This relies at least in part on the coordinated action of liver-enriched transcription factors (LETFs), but little is known about the dynamics of this coordination. In this context we inv...

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Main Authors: Beaudry, Jean-Bernard, Pierreux, Christophe E., Hayhurst, Graham P., Plumb-Rudewiez, Nicolas, Weiss, Mary C., Rousseau, Guy G., Lemaigre, Frédéric P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592803/
https://ncbi.nlm.nih.gov/pubmed/16880515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02445-05
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