Control of liver cell fate decision by a gradient of TGFβ signaling modulated by Onecut transcription factors

During liver development, hepatocytes and biliary cells differentiate from common progenitors called hepatoblasts. The factors that control hepatoblast fate decision are unknown. Here we report that a gradient of activin/TGFβ signaling controls hepatoblast differentiation. High activin/TGFβ signalin...

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Detaylı Bibliyografya
Asıl Yazarlar: Clotman, Frédéric, Jacquemin, Patrick, Plumb-Rudewiez, Nicolas, Pierreux, Christophe E., Van der Smissen, Patrick, Dietz, Harry C., Courtoy, Pierre J., Rousseau, Guy G., Lemaigre, Frédéric P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2005
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186184/
https://ncbi.nlm.nih.gov/pubmed/16103213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.340305
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