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Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9

BACKGROUND AND AIMS: A number of diseases are characterized by defective formation of the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to cholangiocytes which give rise to the intrahepatic bile ducts. Here we investigated how these ducts develop in mouse liver and characterized...

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Detalhes bibliográficos
Main Authors: Antoniou, Aline, Raynaud, Peggy, Cordi, Sabine, Zong, Yiwei, Tronche, François, Stanger, Ben, Jacquemin, Patrick, Pierreux, Christophe E., Clotman, Frederic, Lemaigre, Frederic P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743481/
https://ncbi.nlm.nih.gov/pubmed/19403103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.02.051
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