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Notch signaling controls liver development by regulating biliary differentiation

In the mammalian liver, bile is transported to the intestine through an intricate network of bile ducts. Notch signaling is required for normal duct formation, but its mode of action has been unclear. Here, we show in mice that bile ducts arise through a novel mechanism of tubulogenesis involving se...

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Detalhes bibliográficos
Main Authors: Zong, Yiwei, Panikkar, Archana, Xu, Jie, Antoniou, Aline, Raynaud, Peggy, Lemaigre, Frederic, Stanger, Ben Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673761/
https://ncbi.nlm.nih.gov/pubmed/19369401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.029140
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