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Notch Signaling is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice
BACKGROUND & AIMS: The Notch signaling pathway is activated in leukemia and solid tumors (such as lung cancer), but little is known about its role in liver cancer. METHODS: The intracellular domain of Notch was conditionally expressed in hepatoblasts and their progeny (hepatocytes and cholangioc...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505826/ https://ncbi.nlm.nih.gov/pubmed/22974708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.09.002 |
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