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The Role of Paracrine Signals During Liver Regeneration

During chronic injury a population of bipotent hepatic progenitor cells (HPCs) become activated to regenerate both cholangiocytes and hepatocytes. Here we show in human diseased liver and mouse models of the ductular reaction that Notch and Wnt signaling direct specification of HPCs via their intera...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Stanger, Ben Z., Greenbaum, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671199/
https://ncbi.nlm.nih.gov/pubmed/23038651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25911
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