Suppression of Huntington's disease pathology in Drosophila by human single-chain Fv antibodies

Misfolded neuronal proteins have been identified in a number of neurodegenerative disorders and have been implicated in the pathogenesis of diseases that include Alzheimer's disease, Parkinson's disease, prion-based dementia, Huntington's disease (HD), and other polyglutamine diseases...

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Main Authors: Wolfgang, William J., Miller, Todd W., Webster, Jack M., Huston, James S., Thompson, Leslie M., Marsh, J. Lawrence, Messer, Anne
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183604/
https://ncbi.nlm.nih.gov/pubmed/16061794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505321102
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