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Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
B cell homeostasis is maintained by a balance between the continual generation of new cells and their elimination. Here we show proapoptotic BCL-2 family members BAX and BAK are essential for regulating the number of B cells at both immature and mature developmental stages. BAX and BAK are critical...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183578/ https://ncbi.nlm.nih.gov/pubmed/16055554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504783102 |
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