Llwytho...

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease

B cell homeostasis is maintained by a balance between the continual generation of new cells and their elimination. Here we show proapoptotic BCL-2 family members BAX and BAK are essential for regulating the number of B cells at both immature and mature developmental stages. BAX and BAK are critical...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takeuchi, Osamu, Fisher, Jill, Suh, Heikyung, Harada, Hisashi, Malynn, Barbara A., Korsmeyer, Stanley J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183578/
https://ncbi.nlm.nih.gov/pubmed/16055554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504783102
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