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Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice
Cytochrome P450 reductase is the unique electron donor for microsomal cytochrome P450s; these enzymes play a major role in the metabolism of endogenous and xenobiotic compounds. In mice with a liver-specific deletion of cytochrome P450 reductase, hepatic cytochrome P450 activity is ablated, with con...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183466/ https://ncbi.nlm.nih.gov/pubmed/15717863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042087 |
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