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Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice

Cytochrome P450 reductase is the unique electron donor for microsomal cytochrome P450s; these enzymes play a major role in the metabolism of endogenous and xenobiotic compounds. In mice with a liver-specific deletion of cytochrome P450 reductase, hepatic cytochrome P450 activity is ablated, with con...

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Библиографические подробности
Главные авторы: Wang, Xiu Jun, Chamberlain, Mark, Vassieva, Olga, Henderson, Colin J., Wolf, C. Roland
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183466/
https://ncbi.nlm.nih.gov/pubmed/15717863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042087
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