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A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles
Retroviral integration is central to viral persistence and pathogenesis, cancer as well as host genome evolution. However, it is unclear why integration appears essential for retrovirus production, especially given the abundance and transcriptional potential of non-integrated viral genomes. The invo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180852/ https://ncbi.nlm.nih.gov/pubmed/15904533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-31 |
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