Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase

Integration of the HIV-1 DNA into the host genome is essential for viral replication and is catalyzed by the retroviral integrase. To date, the only substrate described to be involved in this critical reaction is the linear viral DNA produced in reverse transcription. However, during HIV-1 infection...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Richetta, Clémence, Thierry, Sylvain, Thierry, Eloise, Lesbats, Paul, Lapaillerie, Delphine, Munir, Soundasse, Subra, Frédéric, Leh, Hervé, Deprez, Eric, Parissi, Vincent, Delelis, Olivier
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2019
主題:
Microbiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527176/
https://ncbi.nlm.nih.gov/pubmed/30971426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006755
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