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Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase
Integration of the HIV-1 DNA into the host genome is essential for viral replication and is catalyzed by the retroviral integrase. To date, the only substrate described to be involved in this critical reaction is the linear viral DNA produced in reverse transcription. However, during HIV-1 infection...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527176/ https://ncbi.nlm.nih.gov/pubmed/30971426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006755 |
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