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Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease

The Runx3 transcription factor is a key regulator of lineage-specific gene expression in several developmental pathways and could also be involved in autoimmunity. We report that, in dendritic cells (DC), Runx3 regulates TGFβ-mediated transcriptional attenuation of the chemokine receptor CCR7. When...

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Detaylı Bibliyografya
Asıl Yazarlar: Fainaru, Ofer, Shseyov, David, Hantisteanu, Shay, Groner, Yoram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180803/
https://ncbi.nlm.nih.gov/pubmed/16027362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504787102
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