Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

RUNX transcription factors are key regulators of lineage-specific gene expression and might be involved in autoimmune diseases. Runx3 plays a role during the development of sensory neurons and T cells and regulates transforming growth factor β (TGF-β) signaling in dendritic cells. Here, we report th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Brenner, Ori, Levanon, Ditsa, Negreanu, Varda, Golubkov, Olga, Fainaru, Ofer, Woolf, Eilon, Groner, Yoram
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15514019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407180101
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