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Loss of Osteoblast Runx3 Produces Severe Congenital Osteopenia
Congenital osteopenia is a bone demineralization condition that is associated with elevated fracture risk in human infants. Here we show that Runx3, like Runx2, is expressed in precommitted embryonic osteoblasts and that Runx3-deficient mice develop severe congenital osteopenia. Runx3-deficient oste...
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| Publicado no: | Mol Cell Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355527/ https://ncbi.nlm.nih.gov/pubmed/25605327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01106-14 |
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