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Runx3 knockouts and stomach cancer: The challenge of identifying phenotypic defects directly attributable to loss of gene function
Gene targeting often results in knockout mice that show several phenotypes, some of which may not directly relate to the intrinsic function of the disrupted gene. Hence, to study the biological function of genes using knockout mice, one must identify the defects that are directly due to the loss of...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1319207/ https://ncbi.nlm.nih.gov/pubmed/12776174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor868 |
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