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In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer

SCID patients have been successfully treated by administration of ex vivo gene-corrected stem cells. However, despite its proven efficacy, such treatment carries specific risks and difficulties. We hypothesized that some of these drawbacks may be overcome by in situ gene correction of T lymphoid pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Adjali, Oumeya, Marodon, Gilles, Steinberg, Marcos, Mongellaz, Cédric, Thomas-Vaslin, Véronique, Jacquet, Chantal, Taylor, Naomi, Klatzmann, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180533/
https://ncbi.nlm.nih.gov/pubmed/16075064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23966
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