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In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
BACKGROUND: The thymus is the primary site for T-cell development and induction of self-tolerance. Previous approaches towards manipulation of T-cell differentiation have used intrathymic injection of antigens, as proteins, cells or adenoviruses, leading to transient expression of the foreign protei...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516029/ https://ncbi.nlm.nih.gov/pubmed/15318949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-5-18 |
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